Can cardiologists distinguish innocent from pathologic murmurs in neonates?
Mackie, AS. et al.
J Pediatr 2009;154:50-4.
n-201
5 cardiologists
After clinical exam, documented murmur as "likely innocent" or "likely pathologic".
After EKG, the documentation was repeated.
Echocardiogram was taken as gold-standard.
Age 2-31 days (median 12 day)
113/201 had heart defect (56%)
Clinical assessment: Senstivity 80.5%, Specificity 90.9%
Positive predictive value 91.9%
Negative predictive value 78.4%
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