Showing posts with label Pulmonary Hypertension. Show all posts
Showing posts with label Pulmonary Hypertension. Show all posts

Tuesday, June 16, 2015

Pulmonary arterial capacitance

Pulmonary arterial capacitance is an important predictor of mortality in heart failure with a preserved ejection fraction.
Al-Naamani et al. JACC: Heart Failure 2015;3(6):467-74.

Several definitions are explained in the introduction of this article.
Pulmonary hypertension secondary left heart disease is defined as mean PAP > 25 mmHg and mean PAWP > 15 mmHg.

Transpulmonary gradient > 12 mmHg is considered "disproportionate" increase in mean PAP relative to mean PAWP.

These two groups (disproportionate vs. proportionate increase in mPAP) may be better discriminated by diastolic pressure gradient > or = 7 mmHg vs. < 7 mmHg (ref:  Vachiery JL et al. Pulmonary hypertension due to left heart disease. JACC 2013 Dec;62(25 Suppl):D100-8).