Cardiac outcomes in young adult survivors of the arterial switch operation for transposition of the great arteries.
Daniel Tobler, William G. Williams, Anusha Jegatheeswaran, et al.
JACC 2010;56(1):58-64.
Article
132 infants discharges from Toronto before 1991.
97% survival at 20 yrs.
65 were followed in Toronto are the study population.
Outcome:
11 pts (17%) had at least one clinically significant lesion (Ventricular dysfunction, valvular dysfunction or arrhythmia)
Residual lesions are more common in patients who needed cath interventions during childhood (Odds ratio 10.7).
5 pts (8%) had arrhythmia.
7 (11%) needed reintervention (5 reops & 2 Pacemaker placements)
No intervention was necessary for AR or Aortic root dilatation.
Exercise capacity was reduced in 82% of survivors.
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