Sunday, September 13, 2015

Congenital heart defects and receipt of special education services

Tiffany Riehle-Colarusso et al.
Pediatrics 2015;136:496-503.

Compared with children without birth defects, children with CHD were 50% more likely to receive special education services (Adjusted Prevalence Rate Ratio 1.5)

Special education categories:
Intellectual disability (aPRR 3.8)
Sensory impairment (aPRR 3.0)
Other health impairment (aPRR 2.8)
Significant developmental delay (aPRR 1.9)
Specific learning disability (1.4)

Saturday, August 22, 2015

Sildenafil - liquid preparation

Click on the image to enlarge
(10 mg/ml)


New therapy for high LDL - PCSK9 inhibitor

From an advertisement by AmGen in Cardiology News August 2015:
New therapy for high LDL level.
PCSK9 inhibitor
PCSK9 (Proprotein convertase subtilisin/kexin type 9) degrades LDL receptors in hepatocytes.
Injection Praluent (Alirocumab) 75 mg or 150 mg. self-administer, q2weeks, recently approved by FDA.



Hyperkalemia therapy - Patriomer

From Cardiology News Aug 2015
Patiromer - a pottasium binding polymer. Binds with K in GI tract and enables excretion in stool.
JAMA 2015:314:129-30.

New Heart Failure Medication - Sacubitril (Neprilysin inhibitor)

From Cardiology News Aug 2015:
RE: FDA approval for a combination medication (Sacubitril + Valsartan)
Sacubitril - a neprilysin inhibitor
Valsartaion - an angiotensin receptor blocker

Tuesday, June 16, 2015

ARVD criteria

Importance of CMR within the task force criteria for the diagnosis of ARVC in children and adolescents.
Etoom Y, et al. JACC 2015;65:987-995.