Article
Arch Dis Child Fetal Neonatal Ed 2008'93:F257-F260.
49 infants were analyzed (median GA 30 wks, weight 1220g)
18 had hemodynamically-significant PDA - Day 3 NT-proBNP was high (median 32,907 pg/ml; Range: 11,396 - 127,155 pg/ml).
31 controls (no PDA, no Sepsis) - Day 3 median NT-pro-BNP was 3147 pg/ml (Range: 521 - 10,343 pg/ml).
Cut-off value for Day 3, NT-pro-BNP is 11,395 pg/ml for hemodynamically-significant PDA (Sensitivity 100% and Specificity 95%)
Sepsis: Day 10 NT-pro-BNP was elevated in infants who developed sepsis. Animal studies suggest that inflammatory cytokines may stimulate production and release of BNP during sepsis.
Showing posts with label BNP. Show all posts
Showing posts with label BNP. Show all posts
Monday, February 21, 2011
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