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(10 mg/ml)
Saturday, August 22, 2015
New therapy for high LDL - PCSK9 inhibitor
From an advertisement by AmGen in Cardiology News August 2015:
New therapy for high LDL level.
PCSK9 inhibitor
PCSK9 (Proprotein convertase subtilisin/kexin type 9) degrades LDL receptors in hepatocytes.
Injection Praluent (Alirocumab) 75 mg or 150 mg. self-administer, q2weeks, recently approved by FDA.
Hyperkalemia therapy - Patriomer
From Cardiology News Aug 2015
Patiromer - a pottasium binding polymer. Binds with K in GI tract and enables excretion in stool.
JAMA 2015:314:129-30.
New Heart Failure Medication - Sacubitril (Neprilysin inhibitor)
From Cardiology News Aug 2015:
RE: FDA approval for a combination medication (Sacubitril + Valsartan)
Sacubitril - a neprilysin inhibitor
Valsartaion - an angiotensin receptor blocker
